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Microbial Fermentation

BioVectra is an industry leader in microbial fermentation, with 64,000 L of fermentation capacity.

Types of Drug Products:

  • Small molecules
  • Proteins
  • Enzymes
  • Antibody fragments
  • Peptides
Range of Microbes:

  • Filamentous bacteria
  • Marine based bacteria
  • Fungal fermentation
  • E. Coli
Downstream Processing:

  • Centrifugations
  • Lysis
  • Purification
  • UF/DF
  • Synthetic chemistry

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Complex Chemistry

BioVectra’s complex chemistry expertise includes:

  • Wide-ranging synthetic chemistry capabilities
  • Normal phase and reversed phase purification capabilities
  • Potent chemistry (occupational exposure limit levels of < 20 ng/m3)
  • Small molecule capture methods supporting downstream processing
  • Instrumental tools for reaction design and monitoring

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High Potency APIs

BioVectra’s fermentation and chemical processing suites are equipped to handle the development and cGMP scale-up of High Potency APIs (HPAPIs). We have experience handling potent substances with occupational exposure limit (OEL) levels of < 20 ng/m3 (Safebridge Band 3 and 4).

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Our distinct Microbial Biologics facility in Windsor, Nova Scotia, Canada is equipped to work with a range of biosafety level one (BSL-1) expression systems, including

  • E. Coli
  • Pichia Pastoris
  • Saccharomyces Cerevisiae

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Process & Analytical Development

Process and analytical development at BioVectra includes:

  • Pre-clinical, clinical phase I-III and commercial
  • Technology transfer of process and methods
  • Process scale-up from milligram to metric ton quantities
  • Analytical method development and validation
  • Phase appropriate cGMP and Quality by Design (QbD)
  • Life-cycle management approach

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Drug Development

BioVectra’s drug development activities capitalize on our experience, expertise and capabilities, with specific focus on:

  • Mircobial fermentation
  • Complex chemical synthesis
  • Complex IV and IM formulations
    • Nanoparticulate formulations, controlled release, high potency APIs

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BioVectra is a leading supplier of high quality reagents to the pharmaceutical and biotechnology industries. Our reagents include:

Bioprocessing Reagents: Diagnostic Reagents: Molecular Biology Reagents: MPEG Reagents:
  • DTT
  • DTE
  • DHAA
  • PEP-K
  • pNPP-Na
  • GPNA
  • X-Gal
  • BCIP-Na
  • XTT
  • Maleimides
  • Propionaldehydes
  • Amines

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What’s New



  • DCAT Week 2020

    To set up a meeting with us at DCAT Week, email: info@biovectra.com

Schedule a Meeting!


Facilitiy Overview

  • 110,000 Square feet manufacturing facility space
  • 50,000 L of chemical reactor space (20 L to 18,000 L)
  • 64,000 L of fermentation reactor space (30 L to 17,000 L)